A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents

  • Ayana Melaku Yadessa Department of Chemistry, School of Applied Natural Sciences, Adama Science and Technology University, Ethiopia; Email: yadessamelaku2010@gmail.com
  • Digafie Zeleke Adama Science and Technology University

Abstract

Numerous natural products possessing quinoline moiety exhibit interesting biological and pharmacological properties, such as antimalarial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory, immunosuppressive, antileishmanial, and anticancer  activity. Surprising, quinoline scaffold has been used to synthesize antimalarial, antibacterial and anticancer drugs. This article provides update on the latest development in synthesis and biological evaluation of antimalarial, antibacterial and anticancer quinoline analogs. The new synthetic methodologies and the biological activities of the new quinoline analogs in the three areas were focused.

Key words: antimalarial, antibacterial, anticancer and quinoline

Published
2021-06-29
How to Cite
Yadessa, A., & Zeleke, D. (2021). A Review on Synthesis of Quinoline Analogs as Antimalarial, Antibacterial and Anticancer agents. Ethiopian Journal of Sciences and Sustainable Development, 8(2), 73-95. https://doi.org/10.20372/ejssdastu:v8.i2.2021.368
Section
Articles